America’s first and only
3,260 mile
ultra relay run!
MS Run the US fuels hope for people impacted by multiple sclerosis (MS) by raising awareness and funds to advance research, provide resources and promote wellbeing.
Apply To Run The Ultra Relay
Apply To Run The Ultra Relay
Our Ultra Relay is an epic cross-country relay run from California to New York supporting the multiple sclerosis community, with only 21 spots available each year. Want a spot on the team? Apply to run the relay and be part of the next journey across America.
JOIN OUR RUNNING COMMUNITY
JOIN OUR RUNNING COMMUNITY
Each year we run 3,260 miles across America, but that’s not all we do! Sign up to join our community of amazing individuals that support our mission all year long through our exciting and inclusive nationwide programs and events!
RUN FOR A REASON
Every year we run across America and rally thousands in support to help STOP multiple sclerosis (MS)! This is our story and why we run for a reason. Join us!




